For setting up the QuickBooks Payroll, you need to begin with your payroll setup in such a way that makes your payroll set up totally painless. You need to add business and employee details to make the pay checks in the QuickBooks and then print it or write it on the checks. Then you will be taken back to the set up and then begin with the set up of the second step. Here, you need to complete your payroll setup tasks by selecting the option of Overview and starting with your task.